Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
Zf, M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the Central region of human AGR2.
anticorps AG2, anticorps GOB-4, anticorps HAG-2, anticorps PDIA17, anticorps XAG-2, anticorps Agr2h, anticorps Gob-4, anticorps mAG-2, anticorps wu:fj29g05, anticorps zgc:112187, anticorps agr2, anticorps hag3, anticorps hag-3, anticorps bcmp11, anticorps MGC89004, anticorps XAgr2, anticorps agr2-A, anticorps anterior gradient 2, protein disulphide isomerase family member, anticorps anterior gradient 2, anticorps anterior gradient 3, protein disulphide isomerase family member, anticorps anterior gradient 2, protein disulphide isomerase family member S homeolog, anticorps AGR2, anticorps Agr2, anticorps agr2, anticorps agr3, anticorps agr2.S
Sujet
Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.