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SUV420H2/KMT5C anticorps (AA 187-214)

SUV420H2 Reactivité: Souris, Humain WB, FACS Hôte: Lapin Polyclonal RB19392 unconjugated
N° du produit ABIN390405
  • Antigène Voir toutes SUV420H2/KMT5C (SUV420H2) Anticorps
    SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))
    Épitope
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 187-214
    Reactivité
    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    Souris, Humain
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 20
    • 1
    • 1
    Polyclonal
    Conjugué
    • 13
    • 4
    • 3
    • 1
    • 1
    Cet anticorp SUV420H2/KMT5C est non-conjugé
    Application
    • 17
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Homologie
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids of human SUV4-20H2.
    Clone
    RB19392
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SUV420H2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Boonsanay, Zhang, Georgieva, Kostin, Qi, Yuan, Zhou, Braun: "Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation." dans: Cell stem cell, Vol. 18, Issue 2, pp. 229-42, (2016) (PubMed).

  • Antigène
    SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))
    Autre désignation
    SUV4-20H2 (SUV420H2 Produits)
    Synonymes
    anticorps zgc:162876, anticorps KMT5C, anticorps BC024816, anticorps Suv4-20h2, anticorps lysine methyltransferase 5C, anticorps suppressor of variegation 4-20 homolog 2 (Drosophila), anticorps lysine (K)-specific methyltransferase 5C L homeolog, anticorps KMT5C, anticorps kmt5c, anticorps SUV420H2, anticorps kmt5c.L, anticorps Kmt5c
    Sujet
    SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
    Poids moléculaire
    52113
    ID gène
    84787
    NCBI Accession
    NP_116090
    UniProt
    Q86Y97
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