HFE anticorps (AA 122-148)

N° du produit ABIN390457

Cet anticorps Lapin Polyclonal détecte spécifiquement HFE dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour HFE anticorps (AA 122-148) (ABIN390457)

Antigène: HFE (Hemochromatosis (HFE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HFE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19120

Détail du produit anti-HFE anticorps

Épitope: AA 122-148

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This HFE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human HFE.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur HFE

Antigène: HFE (Hemochromatosis (HFE))

Autre désignation: HFE

Sujet: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.

Poids moléculaire: 40108

ID gène: 3077

NCBI Accession: NP_000401, NP_620572, NP_620573, NP_620575, NP_620576, NP_620577, NP_620578, NP_620579, NP_620580

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process