XPO1 anticorps (C-Term)

N° du produit ABIN390636

Cet anticorps anti-XPO1 est un anticorps Lapin Polyclonal détectant XPO1 dans FACS et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour XPO1 anticorps (C-Term) (ABIN390636)

Antigène: XPO1 (Exportin 1 (XPO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPO1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19972

Détail du produit anti-XPO1 anticorps

Épitope: AA 817-846, C-Term

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-XPO1 (ABIN390636)

Sharma, Åkerström, Sharma, Chow, Teow, Abrenica, Booth, Booth, Mirazimi, Lal: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." dans: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).

Détails sur XPO1

Antigène: XPO1 (Exportin 1 (XPO1))

Autre désignation: XPO1

Sujet: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Poids moléculaire: 123386

ID gène: 7514

NCBI Accession: NP_003391

UniProt: O14980

Pathways: M Phase