GSTM1 anticorps (C-Term)

N° du produit ABIN390883

Cet anticorps Lapin Polyclonal détecte spécifiquement GSTM1 dans WB, IHC (p) et FACS. Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour GSTM1 anticorps (C-Term) (ABIN390883)

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB21078

Détail du produit anti-GSTM1 anticorps

Épitope: AA 184-211, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-211 amino acids from the C-terminal region of human GSTM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GSTM1 (ABIN390883)

Engman, Varghese, Lagerstedt Robinson, Malmgren, Hammarsjö, Byström, Lalitkumar, Gemzell-Danielsson: "GSTM1 gene expression correlates to leiomyoma volume regression in response to mifepristone treatment." dans: PLoS ONE, Vol. 8, Issue 12, pp. e80114, (2013) (PubMed).

Détails sur GSTM1

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Autre désignation: GSTM1

Sujet: GSTM1 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Poids moléculaire: 25712

ID gène: 2944

NCBI Accession: NP_000552, NP_666533

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity