GSTM1 anticorps (C-Term)

N° du produit ABIN390883

Détail du produit anti-GSTM1 anticorps

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Épitope: AA 184-211, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-211 amino acids from the C-terminal region of human GSTM1.

Clone: RB21078

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GSTM1 (ABIN390883)

Engman, Varghese, Lagerstedt Robinson, Malmgren, Hammarsjö, Byström, Lalitkumar, Gemzell-Danielsson: "GSTM1 gene expression correlates to leiomyoma volume regression in response to mifepristone treatment." dans: PLoS ONE, Vol. 8, Issue 12, pp. e80114, (2013) (PubMed).

Détails sur GSTM1

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Autre désignation: GSTM1 (GSTM1 Produits)

Synonymes: anticorps GST1, anticorps GSTM1-1, anticorps GSTM1a-1a, anticorps GSTM1b-1b, anticorps GTH4, anticorps GTM1, anticorps H-B, anticorps MU, anticorps MU-1, anticorps GSTA3, anticorps Gstb-1, anticorps Gstb1, anticorps gst-mu, anticorps gst1, anticorps gstm1, anticorps gstm2, anticorps gth4, anticorps gtm1, anticorps glutathione S-transferase mu 1, anticorps glutathione S-transferase M1, anticorps glutathione S-transferase, mu 1, anticorps glutathione S-transferase Mu 1, anticorps glutathione S-transferase mu 2 (muscle), anticorps glutathione S-transferase mu 1 L homeolog, anticorps GSTM1, anticorps Gstm1, anticorps LOC100356307, anticorps GSTM2, anticorps LOC100731426, anticorps gstm1.L

Sujet: GSTM1 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Poids moléculaire: 25712

ID gène: 2944

NCBI Accession: NP_000552, NP_666533

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity