PKC mu anticorps (N-Term)

N° du produit ABIN391011

Cité dans 3 publications. Cet anticorps anti-PKC mu Polyclonal Lapin (Clone RB1037) (ABIN391011) détecte spécifiquement PKC mu dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PKC mu anticorps (N-Term) (ABIN391011)

Antigène: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC mu est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1037

Détail du produit anti-PKC mu anticorps

Épitope: AA 361-389, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PKC mu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-389 amino acids from the N-terminal region of human PKC mu.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PKC mu (ABIN391011)

Spratley, Bastea, Döppler, Mizuno, Storz: "Protein kinase D regulates cofilin activity through p21-activated kinase 4." dans: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 34254-61, (2011) (PubMed).

Ivanova, Atanasova, Poumay, Mitev: "Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation." dans: Archives of dermatological research, Vol. 300, Issue 3, pp. 139-45, (2008) (PubMed).

Wu, Solaro: "Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins." dans: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30691-8, (2007) (PubMed).

Détails sur PKC mu

Antigène: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Autre désignation: PKC mu

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC mu is one of the PKC family members. The protein is a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.

Poids moléculaire: 101704

ID gène: 5587

NCBI Accession: NP_002733

UniProt: Q15139

Pathways: Myometrial Relaxation and Contraction