DTYMK anticorps (C-Term)

N° du produit ABIN391075

Cet anticorps Lapin Polyclonal détecte spécifiquement DTYMK dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DTYMK anticorps (C-Term) (ABIN391075)

Antigène: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DTYMK est non-conjugé

Application: Western Blotting (WB)

Clone: RB5576

Détail du produit anti-DTYMK anticorps

Épitope: AA 164-194, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This DTYMK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the C-terminal region of human DTYMK.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur DTYMK

Antigène: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Autre désignation: DTYMK

Sujet: Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Poids moléculaire: 23819

ID gène: 1841

NCBI Accession: NP_036277

UniProt: P23919

Pathways: Nucleotide Phosphorylation