CKM anticorps (C-Term)

N° du produit ABIN391096

Cet anticorps Lapin Polyclonal détecte spécifiquement CKM dans WB, FACS et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour CKM anticorps (C-Term) (ABIN391096)

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKM est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB5382

Détail du produit anti-CKM anticorps

Épitope: AA 283-313, C-Term

Homologie: B, Pig, Rb

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CKM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the C-terminal region of human CKM.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CKM (ABIN391096)

Yang, Fann, Chang, Tai, Jiang, Kao: "Regulation of sodium-calcium exchanger activity by creatine kinase under energy-compromised conditions." dans: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28275-85, (2010) (PubMed).

Détails sur CKM

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Autre désignation: CKM

Sujet: Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Poids moléculaire: 43101

ID gène: 1158

NCBI Accession: NP_001815

UniProt: P06732