STK38 anticorps (C-Term)

N° du produit ABIN391097

L’anticorps anti-STK38 Polyclonal Lapin est utilisé pour la détection de STK38 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour STK38 anticorps (C-Term) (ABIN391097)

Antigène: STK38 (serine/threonine Kinase 38 (STK38))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK38 est non-conjugé

Application: Western Blotting (WB)

Clone: RB9191

Détail du produit anti-STK38 anticorps

Épitope: AA 410-439, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This STK38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human STK38.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur STK38

Antigène: STK38 (serine/threonine Kinase 38 (STK38))

Autre désignation: STK38

Sujet: Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.

Poids moléculaire: 54190

ID gène: 11329

NCBI Accession: NP_009202

UniProt: Q15208