ADK anticorps (C-Term)

N° du produit ABIN391132

Cet anticorps Lapin Polyclonal détecte spécifiquement ADK dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour ADK anticorps (C-Term) (ABIN391132)

Antigène: ADK (Adenosine Kinase (ADK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB05395

Détail du produit anti-ADK anticorps

Épitope: AA 322-352, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ADK (ABIN391132)

Annes, Ryu, Lam, Carolan, Utz, Hollister-Lock, Arvanites, Rubin, Weir, Melton: "Adenosine kinase inhibition selectively promotes rodent and porcine islet ?-cell replication." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 10, pp. 3915-20, (2012) (PubMed).

Détails sur ADK

Antigène: ADK (Adenosine Kinase (ADK))

Autre désignation: ADK

Sujet: Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.

Poids moléculaire: 40545

ID gène: 132

NCBI Accession: NP_001114, NP_001189378, NP_001189379, NP_006712

UniProt: P55263

Pathways: Ribonucleoside Biosynthetic Process