PNCK anticorps (C-Term)

N° du produit ABIN391139

2+ publications sont disponibles pour ce produit. L’anticorps anti-PNCK Polyclonal produit chez le Lapin a été validé pour WB et IHC (p). Il convient pour la détection de PNCK dans des échantillons provenant de Humain. }

Aperçu rapide pour PNCK anticorps (C-Term) (ABIN391139)

Antigène: PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNCK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1253-1254

Détail du produit anti-PNCK anticorps

Épitope: AA 314-343, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PNCK (ABIN391139)

Deb, Zuo, Wang, Barndt, Cheema, Sengupta, Coticchia, Johnson: "Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." dans: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).

Deb, Coticchia, Barndt, Zuo, Dickson, Johnson: "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation." dans: American journal of physiology. Cell physiology, Vol. 295, Issue 2, pp. C365-77, (2008) (PubMed).

Détails sur PNCK

Antigène: PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))

Autre désignation: PNCK

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Poids moléculaire: 38500

ID gène: 139728

NCBI Accession: NP_001034671, NP_001129212

UniProt: Q6P2M8