LRRK1 anticorps (C-Term)

N° du produit ABIN391141

Cet anticorps Lapin Polyclonal détecte spécifiquement LRRK1 dans WB. Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour LRRK1 anticorps (C-Term) (ABIN391141)

Antigène: LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRK1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB6531

Détail du produit anti-LRRK1 anticorps

Épitope: AA 1981-2015, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This LRRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1981-2015 amino acids from the C-terminal region of human LRRK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-LRRK1 (ABIN391141)

Toyofuku, Morimoto, Sasawatari, Kumanogoh: "Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation." dans: Molecular and cellular biology, Vol. 35, Issue 17, pp. 3044-58, (2015) (PubMed).

Détails sur LRRK1

Antigène: LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))

Autre désignation: LRRK1

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Poids moléculaire: 225393

ID gène: 79705

NCBI Accession: NP_078928

UniProt: Q38SD2