Myosin IA anticorps (AA 276-304)

N° du produit ABIN391517

Détail du produit anti-Myosin IA anticorps

Antigène: Myosin IA (MYO1A)

Épitope: AA 276-304

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin IA est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MYO1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human MYO1A.

Clone: RB19125

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Myosin IA

Antigène: Myosin IA (MYO1A)

Autre désignation: MYO1A (MYO1A Produits)

Synonymes: anticorps CG7438, anticorps Dm IA, anticorps DmIA, anticorps Dmel\\CG7438, anticorps DroMIA, anticorps IA, anticorps MYOIA, anticorps Myo-IA, anticorps Myo1A, anticorps MyoIA, anticorps MyoID, anticorps myoID, anticorps souther, anticorps bbmi, anticorps mihc, anticorps myhl, anticorps dfna48, anticorps MGC83822, anticorps MYO1A, anticorps MGC79641, anticorps BBMI, anticorps DFNA48, anticorps MIHC, anticorps MYHL, anticorps BBM-I, anticorps Myhl, anticorps Myh1, anticorps Myosin 31DF, anticorps myosin IA L homeolog, anticorps myosin IA, anticorps Myo31DF, anticorps myo1a.L, anticorps MYO1A, anticorps myo1a, anticorps Myo1a

Sujet: MYO1A belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein envelops an actin core bundle that, by comparison, is static in structure.

Poids moléculaire: 118401

ID gène: 4640

NCBI Accession: NP_001242970, NP_005370

UniProt: Q9UBC5

Pathways: Sensory Perception of Sound