Tyrosinase-Related Protein 1 anticorps (AA 198-227)

N° du produit ABIN391549

Cet anticorps Lapin Polyclonal détecte spécifiquement Tyrosinase-Related Protein 1 dans FACS, WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (AA 198-227) (ABIN391549)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19412

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Épitope: AA 198-227

Homologie: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CATB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human CATB.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Tyrosinase-Related Protein 1 (ABIN391549)

Jensen, Petterson, Halle, Aaberg-Jessen, Kristensen: "Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo." dans: BMC cancer, Vol. 17, Issue 1, pp. 178, (2018) (PubMed).

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: CATB

Sujet: The protein CATB is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors.

Poids moléculaire: 37822

ID gène: 1508

NCBI Accession: NP_001899, NP_680090, NP_680091, NP_680092, NP_680093

UniProt: P07858