Cathepsin K anticorps (AA 207-237)

N° du produit ABIN391570

Cet anticorps Lapin Polyclonal détecte spécifiquement Cathepsin K dans WB, IHC (p) et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Cathepsin K anticorps (AA 207-237) (ABIN391570)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB19254

Détail du produit anti-Cathepsin K anticorps

Épitope: AA 207-237

Homologie: B, Pr, Pig, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CTSK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human CTSK.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: CTSK

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Poids moléculaire: 36966

ID gène: 1513

NCBI Accession: NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades