Vinculin anticorps (C-Term)
Aperçu rapide pour Vinculin anticorps (C-Term) (ABIN391626)
Antigène
Voir toutes Vinculin (VCL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1012-1039, C-Term
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Homologie
- C, Pig, Rat
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This VINC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1039 amino acids from the C-terminal region of human VINC.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- Vinculin (VCL)
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Autre désignation
- Vinculin
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Sujet
- VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.
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Poids moléculaire
- 123799
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ID gène
- 7414
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NCBI Accession
- NP_003364, NP_054706
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UniProt
- P18206
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Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Antigène
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