CDK10 anticorps (N-Term)

N° du produit ABIN391741

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK10 dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour CDK10 anticorps (N-Term) (ABIN391741)

Antigène: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3172

Détail du produit anti-CDK10 anticorps

Épitope: AA 1-32, N-Term

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CDK10 (ABIN391741)

Hong, Zhang, You, Qiu, Giuliano, Cui, Zhang, Cui: "Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study." dans: BMC cancer, Vol. 15, pp. 548, (2015) (PubMed).

You, Li, Qin, Zhang, Song, Ran, Gao: "Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report." dans: Cellular oncology (Dordrecht), Vol. 38, Issue 6, pp. 485-91, (2015) (PubMed).

Leman, Magheli, Yong, Netto, Hinz, Getzenberg: "Identification of nuclear structural protein alterations associated with seminomas." dans: Journal of cellular biochemistry, Vol. 108, Issue 6, pp. 1274-9, (2009) (PubMed).

Iorns, Turner, Elliott, Syed, Garrone, Gasco, Tutt, Crook, Lord, Ashworth: "Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer." dans: Cancer cell, Vol. 13, Issue 2, pp. 91-104, (2008) (PubMed).

Détails sur CDK10

Antigène: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Autre désignation: CDK10

Sujet: CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.

Poids moléculaire: 41038

ID gène: 8558

NCBI Accession: NP_001092003, NP_001153839, NP_443713, NP_443714

UniProt: Q15131