MAK anticorps (C-Term)

N° du produit ABIN391782

Cité dans 2 publications. Cet anticorps anti-MAK Polyclonal Lapin (Clone RB3342) (ABIN391782) détecte spécifiquement MAK dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAK anticorps (C-Term) (ABIN391782)

Antigène: MAK (Male Germ Cell-Associated Kinase (MAK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3342

Détail du produit anti-MAK anticorps

Épitope: AA 578-608, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-608 amino acids from the C-terminal region of human MAK.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MAK (ABIN391782)

Li, Rao, Zheng-Le, Hurd, Lillo, Khanna: "Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice." dans: Cytoskeleton (Hoboken, N.J.), (2015) (PubMed).

Tucker, Scheetz, Mullins, DeLuca, Hoffmann, Johnston, Jacobson, Sheffield, Stone: "Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E569-76, (2011) (PubMed).

Détails sur MAK

Antigène: MAK (Male Germ Cell-Associated Kinase (MAK))

Autre désignation: MAK

Sujet: MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.

Poids moléculaire: 70581

ID gène: 4117

NCBI Accession: NP_001229314, NP_001229886, NP_005897

UniProt: P20794