ILK anticorps (N-Term)

N° du produit ABIN391993

Cet anticorps Lapin Polyclonal détecte spécifiquement ILK dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour ILK anticorps (N-Term) (ABIN391993)

Antigène: ILK (Integrin-Linked Kinase (ILK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1668

Détail du produit anti-ILK anticorps

Épitope: AA 11-41, N-Term

Homologie: B, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ILK1/ILK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of mouse ILK1/ILK2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ILK (ABIN391993)

Schramm, Opitz, Thies, Seifert, Moch, Weder, Soltermann: "Prognostic significance of epithelial-mesenchymal transition in malignant pleural mesothelioma." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 37, Issue 3, pp. 566-72, (2010) (PubMed).

Samara, Laguinge, Jessup: "Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling." dans: Cancer research, Vol. 67, Issue 10, pp. 4774-82, (2007) (PubMed).

Détails sur ILK

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: ILK1/ILK2

Sujet: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK encodes a predicted 451-amino acid protein, with an apparent molecular weight of 59 kD. The ILK protein is a serine/threonine protein kinase with 4 ankyrin-like repeats. ILK regulates integrin-mediated signal transduction.

Poids moléculaire: 51373

ID gène: 16202

NCBI Accession: NP_001155196, NP_034692

UniProt: O55222

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration