L’anticorps Lapin Polyclonal anti-MAP3K6 a été validé pour WB et IHC (p). Il convient pour détecter MAP3K6 dans des échantillons de Humain et Souris. Il y a 1 publication disponible.
MAP3K6
(Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))
Reactivité
Humain, Souris
Hôte
Lapin
Clonalité
Polyclonal
Conjugué
Cet anticorp MAP3K6 est non-conjugé
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Clone
RB0946
Épitope
AA 1028-1058, C-Term
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.
MAP3K6
Reactivité: Rat
IHC, WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Han, Oh, Kang, Kim, Seo, Kim, Park, Kim: "Protein profiling in human sera for identification of potential lung cancer biomarkers using antibody microarray." dans: Proteomics, Vol. 9, Issue 24, pp. 5544-52, (2009) (PubMed).
Antigène
MAP3K6
(Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))
Autre désignation
MEKK6
Sujet
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.