PIM1 anticorps

N° du produit ABIN392441

Détail du produit anti-PIM1 anticorps

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PIM1 antibody is generated from rabbits immunized with PIM1 recombinant protein.

Clone: RB15686

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PIM1 (ABIN392441)

Xu, Xiong, Cao, Huang, Wang, You, Zhou, Zheng, Hu, Zhang, Zhao: "PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." dans: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).

Baron, Anastasi, Hyjek, Bies, Reddy, Dong, Joseph, Thirman, Wroblewski, Wolff, Baron: "PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5735-9, (2012) (PubMed).

Détails sur PIM1

Antigène: PIM1 (Pim-1 Oncogene (PIM1))

Autre désignation: PIM1 (PIM1 Produits)

Synonymes: anticorps PIM, anticorps Pim-1, anticorps PIM1, anticorps pim, anticorps pim-1, anticorps pim3, anticorps Pim-1 proto-oncogene, serine/threonine kinase, anticorps proviral integration site 1, anticorps Pim-1 proto-oncogene, serine/threonine kinase L homeolog, anticorps PIM1, anticorps Pim1, anticorps pim1, anticorps pim1.L

Sujet: PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.

Poids moléculaire: 35686

ID gène: 5292

NCBI Accession: NP_001230115, NP_002639

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process