MLK4 anticorps (N-Term)

N° du produit ABIN392542

Détail du produit anti-MLK4 anticorps

Antigène: MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))

Épitope: AA 33-62, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLK4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4.

Clone: RB12543

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MLK4

Antigène: MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))

Autre désignation: MLK4 (KIAA1804 Produits)

Synonymes: anticorps MLK4, anticorps RP5-862P8.2, anticorps dJ862P8.3, anticorps Mlk4, anticorps mKIAA1804, anticorps mitogen-activated protein kinase kinase kinase 21, anticorps MAP3K21, anticorps Map3k21

Sujet: Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30 % of colorectal cancer contain at least one mutation in the tyrosine kinases, sampling of colorect cancer cells suggest an important role of MLK4 in this process.

Poids moléculaire: 113957

ID gène: 84451

NCBI Accession: NP_115811

UniProt: Q5TCX8