PIP5K1B anticorps (N-Term)

N° du produit ABIN392594

Il existe 2+ publications pour ce produit. L’anticorps anti-PIP5K1B Polyclonal Lapin est utilisé pour la détection de PIP5K1B dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour PIP5K1B anticorps (N-Term) (ABIN392594)

Antigène: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIP5K1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1729

Détail du produit anti-PIP5K1B anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PIP5K1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PIP5K1B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PIP5K1B (ABIN392594)

Qin, Li, Pan, Wu: "Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl." dans: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 22544-8, (2009) (PubMed).

Bolomini-Vittori, Montresor, Giagulli, Staunton, Rossi, Martinello, Constantin, Laudanna: "Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module." dans: Nature immunology, Vol. 10, Issue 2, pp. 185-94, (2009) (PubMed).

Détails sur PIP5K1B

Antigène: PIP5K1B (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))

Autre désignation: PIP5K1B

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Poids moléculaire: 61036

ID gène: 8395

NCBI Accession: NP_003549

UniProt: O14986

Pathways: Signalisation PI3K-Akt, Inositol Metabolic Process, Cell-Cell Junction Organization