Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This PIP5K1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PIP5K1B.
PIP5K1B
Reactivité: Humain, Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Qin, Li, Pan, Wu: "Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl." dans: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 22544-8, (2009) (PubMed).
Bolomini-Vittori, Montresor, Giagulli, Staunton, Rossi, Martinello, Constantin, Laudanna: "Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module." dans: Nature immunology, Vol. 10, Issue 2, pp. 185-94, (2009) (PubMed).
Antigène
PIP5K1B
(Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, beta (PIP5K1B))
anticorps MSS4, anticorps STM7, anticorps AI844522, anticorps Pip5k1a, anticorps Pipk5a, anticorps Pipk5b, anticorps MGC80809, anticorps pip5k1b, anticorps zgc:101046, anticorps wu:fj29b05, anticorps wu:fj93b05, anticorps zgc:92316, anticorps phosphatidylinositol-4-phosphate 5-kinase type 1 beta, anticorps phosphatidylinositol-4-phosphate 5-kinase, type 1 beta, anticorps phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog, anticorps phosphatidylinositol-4-phosphate 5-kinase, type I, beta a, anticorps phosphatidylinositol-4-phosphate 5-kinase, type I, beta, anticorps phosphatidylinositol 4-phosphate 5-kinase type-1 beta, anticorps phosphatidylinositol-4-phosphate 5-kinase, type I, beta b, anticorps PIP5K1B, anticorps Pip5k1b, anticorps pip5k1b.L, anticorps pip5k1ba, anticorps pip5k1b, anticorps LOC100472550, anticorps pip5k1bb
Sujet
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.