GRAF anticorps (AA 237-267)

N° du produit ABIN392663

Détail du produit anti-GRAF anticorps

Antigène: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Épitope: AA 237-267

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRAF est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This GRAF (OPHN1L) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-267 amino acids from the Central region of human GRAF (OPHN1L).

Clone: RB3722

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur GRAF

Antigène: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Autre désignation: GRAF (OPHN1L) (ARHGAP26 Produits)

Synonymes: anticorps ARHGAP26, anticorps GRAF, anticorps GRAF1, anticorps OPHN1L, anticorps OPHN1L1, anticorps 1810044B20Rik, anticorps 2610010G17Rik, anticorps 4933432P15Rik, anticorps AI853435, anticorps mKIAA0621, anticorps Rho GTPase activating protein 26, anticorps ARHGAP26, anticorps Arhgap26

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Poids moléculaire: 92235

ID gène: 23092

NCBI Accession: NP_001129080, NP_055886

UniProt: Q9UNA1