ULK2 anticorps (C-Term)

N° du produit ABIN392693

L’anticorps Lapin Polyclonal anti-ULK2 a été validé pour WB. Il convient pour détecter ULK2 dans des échantillons de Humain et Souris.

Aperçu rapide pour ULK2 anticorps (C-Term) (ABIN392693)

Antigène: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB03022

Détail du produit anti-ULK2 anticorps

Épitope: AA 612-643, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ULK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 612-643 amino acids from the C-terminal region of human ULK2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ULK2

Antigène: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Autre désignation: ULK2

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Two human homologs of the yeast autophagy-specific kinase exist: ULK1(APG1) and ULK2. APG1 plays a critical role in regulating key elements of the autophagy pathway. APG1 stimulates autophagy, leading to autophagy-dependent restriction of cell growth and ultimately cell apoptosis at high levels of activity, and is a negative regulator of mTOR signaling.

Poids moléculaire: 112694

ID gène: 9706

NCBI Accession: NP_001136082, NP_055498

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagy