NPR3 anticorps (N-Term)

N° du produit ABIN392706

Cité dans 2 publications. Cet anticorps anti-NPR3 Polyclonal Lapin (Clone RB03504) (ABIN392706) détecte spécifiquement NPR3 dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NPR3 anticorps (N-Term) (ABIN392706)

Antigène: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPR3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB03504

Détail du produit anti-NPR3 anticorps

Épitope: AA 67-97, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Natriuretic Peptide Receptor C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-97 amino acids from the N-terminal region of human Natriuretic Peptide Receptor C.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:200. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-NPR3 (ABIN392706)

Loo, Shepherd, Mickle, Lorca, Shutov, Usachev, Mohapatra: "The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical G??-dependent modulation of TRPV1 channel." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 35, pp. 11942-55, (2012) (PubMed).

Liu, Abendschein, Woodard, Rossin, McCommis, Zheng, Welch, Woodard: "Molecular imaging of atherosclerotic plaque with (64)Cu-labeled natriuretic peptide and PET." dans: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 51, Issue 1, pp. 85-91, (2010) (PubMed).

Détails sur NPR3

Antigène: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Autre désignation: Natriuretic Peptide Receptor C (NPR3/ANPC)

Sujet: ANPC is a receptor for atrial natriuretic peptide. It does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.

Poids moléculaire: 59808

ID gène: 4883

NCBI Accession: NP_000899, NP_001191304, NP_001191305

UniProt: P17342

Pathways: cAMP Metabolic Process