DGKQ anticorps (C-Term)

N° du produit ABIN392717

Détail du produit anti-DGKQ anticorps

Antigène: DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

Épitope: AA 912-942, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DGKQ est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DGKQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-942 amino acids from the C-terminal region of human DGKQ.

Clone: RB3823

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur DGKQ

Antigène: DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

Autre désignation: DGKQ (DGKQ Produits)

Synonymes: anticorps DAGK, anticorps DAGK4, anticorps DAGK7, anticorps 110kDa, anticorps Dagk4, anticorps Dgkd, anticorps diacylglycerol kinase theta, anticorps diacylglycerol kinase, theta, anticorps diacylglycerol kinase, theta, putative, anticorps DGKQ, anticorps Dgkq, anticorps Smp_163080, anticorps Tsp_13406

Sujet: Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid.The predicted 882-amino acid human DGKQ (DGK-theta) protein is 90 % identical in sequence to the rat homolog. DGK-theta is comprised of a pleckstrin homology domain and the conserved DGK putative catalytic domain. In contrast to other DGK isotypes, DGK-theta contains 3 rather than 2 cysteine-rich zinc-binding domains, an N-terminal proline- and glycine-rich region, and a RAS-associating domain. Highest tissue expression in the rat is in the brain. Defects in eye-specific DAGK genes cause retinal degeneration in Drosophila, thus, DAGK genes are candidates for human eye disease.

Poids moléculaire: 101155

ID gène: 1609

NCBI Accession: NP_001338

UniProt: P52824