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DUSP14 anticorps (N-Term)

DUSP14 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB5911 unconjugated
N° du produit ABIN392877
  • Antigène Voir toutes DUSP14 Anticorps
    DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
    Épitope
    • 13
    • 8
    • 7
    • 7
    • 7
    • 5
    • 2
    • 1
    AA 1-30, N-Term
    Reactivité
    • 58
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 51
    • 6
    • 1
    Lapin
    Clonalité
    • 54
    • 4
    Polyclonal
    Conjugué
    • 26
    • 6
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DUSP14 est non-conjugé
    Application
    • 46
    • 40
    • 27
    • 5
    • 5
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP14.
    Clone
    RB5911
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DUSP14 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
    Autre désignation
    DUSP14 (DUSP14 Produits)
    Synonymes
    anticorps MGC84083, anticorps zgc:101746, anticorps DUSP14, anticorps mkp-l, anticorps mkp6, anticorps MKP-L, anticorps MKP6, anticorps 1110014C10Rik, anticorps 2310042C07Rik, anticorps D11Ertd395e, anticorps Mkp6, anticorps dual specificity phosphatase 14, anticorps dual specificity phosphatase 14 L homeolog, anticorps DUSP14, anticorps dusp14.L, anticorps dusp14, anticorps Dusp14
    Sujet
    DUSP14 is involved in the inactivation of MAP kinases. This protein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 and B7-2 ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.
    Poids moléculaire
    22255
    ID gène
    11072
    NCBI Accession
    NP_008957
    UniProt
    O95147
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