SIK2 anticorps

N° du produit ABIN400680

Détail du produit anti-SIK2 anticorps

Antigène: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIK2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: Synonyms: SIK-2, SNF1LK2, QIK, Serine/threonine-protein kinase SIK2, Salt-inducible protein kinase 2,Serine/threonine-protein kinase SNF1-like kinase 2, Qin-induced kinase

Purification: Affinity Chromatography.

Immunogène: Recombinant Human SIK2.

Clone: S15G10

Isotype: IgG1

Information d'application

Indications d'application: Western blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2 containing 0.09% Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SIK2

Antigène: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Autre désignation: SIK2 (SIK2 Produits)

Synonymes: anticorps PIG33, anticorps SC1, anticorps LOH11CR1I, anticorps QIK, anticorps SNF1LK2, anticorps G630080D20Rik, anticorps Snf1lk2, anticorps RGD1559698, anticorps si:dkey-27p23.1, anticorps snf1lk2a, anticorps SPARC like 1, anticorps salt inducible kinase 2, anticorps salt-inducible kinase 2, anticorps salt-inducible kinase 2a, anticorps SPARCL1, anticorps SIK2, anticorps SLK2, anticorps Sik2, anticorps sik2a

Sujet: Snf1lk2 belongs to the Ser/Thr protein kinase family, AMPK subfamily. It has one proteinkinase domain and one UBA domain. Snf1lk2 requires magnesium as a cofactor andphosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes. This potentiallymodulates the efficiency of insulin signal transduction. It also inhibits CREB activity byphosphorylating and repressing the CREB-specific coactivators, CRTC1-3. Snf1lk2 isactivated by phosphorylation on Thr-175 by STK11 in complex with STE20-relatedadapter-alpha (STRAD alpha) pseudo kinase and CAB39.

UniProt: Q9H0K1