CXCR2 anticorps

N° du produit ABIN400744

Cet anticorps Souris Monoclonal détecte spécifiquement CXCR2 dans FACS et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CXCR2 anticorps (ABIN400744)

Antigène: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR2 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6D499

Détail du produit anti-CXCR2 anticorps

Specificité: This antibody recognizes Interleukin 8 Receptor B (CXCR2/IL8RB).

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: CXCR2, CXCR-2, GRO/MGSA receptor, IL-8 receptor type 2, CDw128b, IL8 receptor beta

Purification: Protein G Chromatography.

Immunogène: L1. 2 cells expressing Human Interleukin-8 Receptor type B (IL8RB).

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry. Immunohistochemistry on Paraffin Sections: 2.5-5.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS without preservatives.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (Add 40-50% Glycerol) at -20 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CXCR2

Antigène: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Autre désignation: CD182 / IL8RB

Sujet: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.Synonyms: CDw128b, CXCR-2, CXCR2, GRO/MGSA receptor, IL-8 receptor type 2, IL8 receptor beta

ID gène: 3579

UniProt: P25025

Pathways: cAMP Metabolic Process