BRCC3 anticorps (N-Term)

N° du produit ABIN400864

Cet anticorps Souris Monoclonal détecte spécifiquement BRCC3 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour BRCC3 anticorps (N-Term) (ABIN400864)

Antigène: BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BRCC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: AT3B1

Détail du produit anti-BRCC3 anticorps

Épitope: AA 1-316, N-Term

Specificité: The antibody recognizes human BRCC3 / BRCC36. Other species not tested.

Attributs du produit: Synonyms: BRCC36, C6.1A, CXorf53, Lys-63-specific deubiquitinase BRCC36, BRCA1-A complex subunitBRCC36, BRISC complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3,BRCA1/BRCA2-containing complex subunit 36

Purification: Protein-G affinity chromatography

Immunogène: Recombinant BRCC36 (1-316 aa) purified from E. coli

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Paraffin Sections: (5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur BRCC3

Antigène: BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))

Autre désignation: BRCC3

Sujet: BRCC3 (BRCC36, BRCA1/BRCA2-containing complex, subunit 36) is a holoenzyme complex containing BRCA1, BRCA2. BRCC36 is an ubiquitin E3 ligase complex that has a role in DNA repair and enhances cellular survival following DNA damage. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint.Synonyms: BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, Lys-63-specific deubiquitinase BRCC36

ID gène: 79184

UniProt: P46736

Pathways: Positive Regulation of Response to DNA Damage Stimulus