ENPP3 anticorps
Aperçu rapide pour ENPP3 anticorps (ABIN400884)
Antigène
Voir toutes ENPP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This Monoclonal antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Attributs du produit
- Synonyms: E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta, Ectonucleotide pyrophosphatase /phosphodiesterase family member 3, Phosphodiesterase I/nucleotide pyrophosphatase 3
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- HEK-293 cells transfected with human CD203c
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Isotype
- IgG1
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Indications d'application
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Flow cytometry. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
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Autre désignation
- CD203c / ENPP3
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Sujet
- CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.Synonyms: E-NPP 3, Ectonucleotide pyrophosphatase / phosphodiesterase family member 3, PD-I beta, PDNP3, Phosphodiesterase I beta, Phosphodiesterase I/nucleotide pyrophosphatase 3
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ID gène
- 5169
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UniProt
- O14638
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Pathways
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
Antigène
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