IL32 anticorps (Isoform 4)
Aperçu rapide pour IL32 anticorps (Isoform 4) (ABIN401103)
Antigène
Voir toutes IL32 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Isoform 4
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Specificité
- This antibody will recognize both native and recombinant Human IL-32A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
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Purification
- Ig Fraction
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Immunogène
- Full length recombinant Human IL-32A protein
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Isotype
- IgG
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Indications d'application
- ELISA: 1:20,000 - 1:100,000, WB: 1:500 - 1:2,000
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Restrictions
- For Research Use only
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Reconstitution
- Restore with 0.1 mL of deionized water (or equivalent).
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Concentration
- 1.0 mg/mL by UV absorbance at 280 nm
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Buffer
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 without preservatives.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- IL32 (Interleukin 32 (IL32))
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Autre désignation
- Interleukin-32 / IL32
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Sujet
- IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32a, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFa and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: IL-32, NK4, Natural killer cells protein 4, TAIF, Tumor necrosis factor alpha-inducing factor
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ID gène
- 9235
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NCBI Accession
- NP_001012649
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UniProt
- P24001
Antigène
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