ZIC2 anticorps (AA 189-206)
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- Antigène Voir toutes ZIC2 Anticorps
- ZIC2
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Épitope
- AA 189-206
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Reactivité
- Humain, Rat, Souris, Chien, Chimpanzé
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZIC2 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is directed against Mouse ZIC2 protein. A BLAST analysis was used to suggest reactivity with this protein from Human, Chimpanzee, Mouse, Rat and Dog based on 100 % homology for the immunogen sequence. Expect cross reactivity with ZIC2 from Chicken, Zebrafish and Frog as the core 16 amino acid residues within the immunogen sequence show very high degrees of homology with ZIC2 from these sources. Cross reactivity with ZIC2 homologues from other sources has not been determined.
- Réactivité croisée (Details)
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Species reactivity (expected):Human, Chimpanzee, Mouse, Rat, Canine, Chicken, Zebrafish, Frog.
Species reactivity (tested):Mouse. - Purification
- Affinity Chromatography
- Immunogène
- Synthetic peptide corresponding amino acids 189-206 of Mouse ZIC-2
- Isotype
- IgG
- Top Product
- Discover our top product ZIC2 Anticorps primaire
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- Indications d'application
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ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
- Buffer
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at-20 °C.
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- Antigène
- ZIC2
- Autre désignation
- ZIC2 (ZIC2 Produits)
- Synonymes
- anticorps HPE5, anticorps Ku, anticorps cb851, anticorps fb26a03, anticorps wu:fb26a03, anticorps zic2, anticorps zic2.1, anticorps hpe5, anticorps hm:zeh0655, anticorps id:ibd5017, anticorps zic2.2, anticorps zic2l, anticorps Zic family member 2, anticorps zinc finger protein of the cerebellum 2, anticorps zic family member 2 (odd-paired homolog, Drosophila), a, anticorps Zic family member 2 L homeolog, anticorps zic family member 2 (odd-paired homolog, Drosophila) b, anticorps ZIC2, anticorps Zic2, anticorps zic2a, anticorps zic2.L, anticorps zic2b
- Sujet
- ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.Synonyms: Zinc finger protein ZIC 2, Zinc finger protein of the cerebellum 2
- ID gène
- 7546
- NCBI Accession
- NP_009060
- UniProt
- O95409
- Pathways
- Tube Formation
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