ZIC2 anticorps (AA 189-206)

N° du produit ABIN401287

Cet anticorps Lapin Polyclonal détecte spécifiquement ZIC2 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Chien et Chimpanzé.

Aperçu rapide pour ZIC2 anticorps (AA 189-206) (ABIN401287)

Antigène: ZIC2

Reactivité: Humain, Rat, Souris, Chien, Chimpanzé

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZIC2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ZIC2 anticorps

Épitope: AA 189-206

Specificité: This antibody is directed against Mouse ZIC2 protein. A BLAST analysis was used to suggest reactivity with this protein from Human, Chimpanzee, Mouse, Rat and Dog based on 100 % homology for the immunogen sequence. Expect cross reactivity with ZIC2 from Chicken, Zebrafish and Frog as the core 16 amino acid residues within the immunogen sequence show very high degrees of homology with ZIC2 from these sources. Cross reactivity with ZIC2 homologues from other sources has not been determined.

Réactivité croisée (Details): Species reactivity (expected):Human, Chimpanzee, Mouse, Rat, Canine, Chicken, Zebrafish, Frog.
Species reactivity (tested):Mouse.

Purification: Affinity Chromatography

Immunogène: Synthetic peptide corresponding amino acids 189-206 of Mouse ZIC-2

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C.

Détails sur ZIC2

Antigène: ZIC2

Autre désignation: ZIC2

Sujet: ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.Synonyms: Zinc finger protein ZIC 2, Zinc finger protein of the cerebellum 2

ID gène: 7546

NCBI Accession: NP_009060

UniProt: O95409

Pathways: Tube Formation