APC1 anticorps (pSer355)

N° du produit ABIN401294

L’anticorps Lapin Polyclonal anti-APC1 a été validé pour WB et EIA. Il convient pour détecter APC1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet et Chimpanzé.

Aperçu rapide pour APC1 anticorps (pSer355) (ABIN401294)

Antigène: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Chimpanzé

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-APC1 anticorps

Épitope: AA 351-359, pSer355

Specificité: This antibody is specific for phosphorylated APC1 protein at the pS355 residue.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine, Chimpanzee, Chicken.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to amino acids 351-359 of Human Apc1 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/10,000 - 1/40,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.55 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur APC1

Antigène: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Autre désignation: APC1 / ANAPC1

Sujet: APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein

ID gène: 64682

NCBI Accession: NP_073153

UniProt: Q9H1A4