CTCFL anticorps (AA 9-26)

N° du produit ABIN401325

Cet anticorps anti-CTCFL Polyclonal Lapin (ABIN401325) détecte spécifiquement CTCFL dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain et Chimpanzé.

Aperçu rapide pour CTCFL anticorps (AA 9-26) (ABIN401325)

Antigène: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Reactivité: Humain, Chimpanzé

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTCFL est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CTCFL anticorps

Épitope: AA 9-26

Specificité: This antibody is directed against the BORIS protein.

Réactivité croisée (Details): Species reactivity (expected):Chimpanzee.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding aa 9-26 of human BORIS protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.28 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur CTCFL

Antigène: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Autre désignation: CTCFL / BORIS

Sujet: BORIS (Brother of the Regulator of Imprinted Sites) also known as CCCTC-binding factor-like protein, is normally only expressed in the testis and expressed in a mutually exclusive manner with CTCF during male germ cell development. However, previous studies have shown that BORIS is abnormally activated in a wide range of human cancers. Expression of BORIS in normally BORIS-negative cells promotes cell growth that may lead to transformation. BORIS maps to the cancer-associated amplification region thought to contain an oncogene or dominant-immortalizing gene. BORIS is a candidate protein for the epigenetic reprogramming factor acting in the male germ line. BORIS is found in both the nucleus and cytoplasm.Synonyms: Brother of the regulator of imprinted sites, CCCTC-binding factor, CT27, CTCF paralog, CTCF-T, CTCF-like protein, Cancer/testis antigen 27, Transcriptional repressor CTCFL, Zinc finger protein CTCF-T

ID gène: 140690

NCBI Accession: NP_542185

UniProt: Q8NI51