DAXX anticorps (AA 261-274)
Aperçu rapide pour DAXX anticorps (AA 261-274) (ABIN401370)
Antigène
Voir toutes DAXX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 261-274
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Specificité
- This antibody is directed against DAXX protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
Purification
- Affinity Purified
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Immunogène
- Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein
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Isotype
- IgG
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Indications d'application
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ELISA: 1/7,000 - 1/45,000. Western Blot: 1/200 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.06 mg/mL (by UV absorbance at 280)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- DAXX (Death-Domain Associated Protein (DAXX))
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Autre désignation
- DAXX
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Sujet
- DAXX, the Death domain-associated protein 6 (also named Fas death domain-associated protein, ETS1-associated protein 1 or EAP1), functions in part as a transcriptional co-repressor through its interaction with a number of nuclear, DNA-associated proteins, such as histone deacetylase II, core histones H2A, H2B, H3 and H4, and Dek, a chromatinassociated protein reported to change the topology of DNA in chromatin in vitro (1). DAXX also interacts with p73, and is involved in the regulation of the cell cycle and apoptosis through transcriptional regulation of p53 and possibly its family members (2).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein
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ID gène
- 1616
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NCBI Accession
- NP_001135441
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UniProt
- Q9UER7
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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