RAB11FIP3 anticorps (C-Term)

N° du produit ABIN401388

Cet anticorps anti-RAB11FIP3 est un anticorps Lapin Polyclonal détectant RAB11FIP3 dans WB et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RAB11FIP3 anticorps (C-Term) (ABIN401388)

Antigène: RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB11FIP3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RAB11FIP3 anticorps

Épitope: C-Term

Specificité: This antibody is directed against FIP3 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Recombinant protein corresponding to amino acids spanning the carboxyl terminal one- third of human FIP3

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/1,000 - 1/3,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.19 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur RAB11FIP3

Antigène: RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))

Autre désignation: RAB11FIP3

Sujet: Rab11 Family-Interacting Protein 3 (FIP3)/Arfophilin-1 and FIP4/Arfophilin-2 are dual effectors for Rab11 and the ADP-ribosylation factor Arf6. Rab11 and Arf6 are involved in membrane delivery from recycling endosomes to the plasma membrane during cytokinesis. The dual Rab11/Arf6 binding proteins, FIP3 and FIP4, function in the delivery of recycling endosomes to the cleavage furrow and are, together with Rab11, essential for completion of abscission, the terminal step of cytokinesis. An interaction between Rab11-FIP3 and ASAP1 has also been identified (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD). ASAP1 is an Arf GTPase-activating protein that has been implicated in the invasive properties of uveal melanoma and mammary carcinoma.Synonyms: ARFO1, Arfophilin-1, Eferin, FIP3-Rab11, KIAA0665, MU-MB-17.148, Rab11 family-interacting protein 3, Rab11-FIP3

ID gène: 9727

NCBI Accession: NP_001135744

UniProt: O75154