SIPA1 anticorps (N-Term)

N° du produit ABIN401404

Cet anticorps Lapin Polyclonal détecte spécifiquement SIPA1 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SIPA1 anticorps (N-Term) (ABIN401404)

Antigène: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIPA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-SIPA1 anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (expected):Human, Rat.
Species reactivity (tested):Mouse.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to a region near the amino terminus of mouse Sipa1

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/20,000. Western Blot: 1/1,000 - 1/5,000. Immunohistochemistry: 1.25 - 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.25 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur SIPA1

Antigène: SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))

Autre désignation: SIPA1 / SPA1

Sujet: Sipa1 (signal-induced proliferation associated gene 1) is a mitogen-induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. Sipa1 is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.Synonyms: GTPase-activating protein Spa-1, Signal-induced proliferation-associated protein 1, Sipa-1, Spa-1, p130 SPA-1

ID gène: 10090

UniProt: P46062

Pathways: Response to Water Deprivation