FAP anticorps (Internal Region)

N° du produit ABIN401429

L’anticorps anti-FAP Polyclonal Lapin est utilisé pour la détection de FAP dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et EIA.

Aperçu rapide pour FAP anticorps (Internal Region) (ABIN401429)

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAP est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-FAP anticorps

Épitope: Internal Region

Specificité: This antibody is known to react with Mouse FAP protein.

Réactivité croisée (Details): Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse.

Purification: Immunoffinity Chromatography.

Immunogène: Synthetic peptide corresponding to an internal region of mouse FAP protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/100000. Western Blot: 1/500-1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.65 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur FAP

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Autre désignation: Seprase / FAP

Sujet: Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.Synonyms: 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease

ID gène: 14089

NCBI Accession: NP_032012

UniProt: P97321

Pathways: Tube Formation