PTENP1 anticorps (N-Term)

N° du produit ABIN401437

Cet anticorps Lapin Polyclonal détecte spécifiquement PTENP1 dans WB et EIA. Il présente une réactivité envers Humain, Chimpanzé, Chien, Macaque, Souris, Rat, Poisson-ballons vert et Poisson zèbre (Danio rerio).

Aperçu rapide pour PTENP1 anticorps (N-Term) (ABIN401437)

Antigène: PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))

Reactivité: Humain, Chimpanzé, Chien, Macaque, Souris, Rat, Poisson-ballons vert, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTENP1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PTENP1 anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Macaque, Chimpanzee, Opossum, Zebrafish, Green pufferfish, Platypus.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Purified peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/160,000. Western Blot: 1/500 to 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.73 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur PTENP1

Antigène: PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))

Autre désignation: PTENP1

Sujet: This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.Synonyms: PTEN-rs, PTEN2, PTH2, Phosphatase and tensin homolog 2, Phosphatase and tensin homolog pseudogene 1, psiPTEN

ID gène: 9606

UniProt: O43460