CA1 anticorps (Internal Region)
Aperçu rapide pour CA1 anticorps (Internal Region) (ABIN401513)
Antigène
Voir toutes CA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Séquence
- c-QAIKTKGKRA P
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Specificité
- This antibody detects internal Carbonic anhydrase 1.
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Réactivité croisée (Details)
- Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human
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Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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Immunogène
- Peptide from the internal region of the protein sequence according to NP_001729.1 . Genename: CA1
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Indications d'application
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Peptide ELISA: antibody detection limit dilution 1: 64000. Western blot: 0.03-0.1 μg/mL. Approx 29 kDa band observed in Human Liver lysates(calculated MW of 28.9 kDa according to NP_001729.1.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- CA1 (Carbonic Anhydrase I (CA1))
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Autre désignation
- Carbonic Anhydrase 1
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Sujet
- Carbonic Anhydrase I (CAI) is a single polypeptide chain metalloenzyme of molecular weight 29 kDa. It is present mainly in erythrocytes at a concentration of about 12 mg per gram haemoglobin. Its main enzyme function is to catalyse the reversible hydration of carbon dioxide. It also catalyses the hydrolysis of certain esters. The twelve active CA isozymes are thought to regulate a variety of cellular functions including several processes in the reproductive systems. A mutational deficiency has been described but patients exhibit no adverse chemical symptoms. Red cell CAI levels are decreased in patients with thyrotoxicosis.Synonyms: CA-I, CA1, CAB, Carbonate dehydratase I, Carbonic anhydrase B, Carbonic anhydrase I
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ID gène
- 759
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NCBI Accession
- NP_001729
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UniProt
- P00915
Antigène
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