HMOX2 anticorps (Internal Region)

N° du produit ABIN401519

Détail du produit anti-HMOX2 anticorps

Antigène: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Épitope: Internal Region

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HMOX2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: c-DQAGSTLARE TLED

Specificité: This antibody detects HMOX2 (Internal).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_002125.3 . Genename: HMOX2

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: Recommended concentration: 0.3-1 μg/mL. Approx 37 kDa band observed inlysates of cell line K562 (calculated MW of 36.7 kDa according to NP_002125.3).

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur HMOX2

Antigène: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Autre désignation: Heme Oxygenase 2 (HMOX2) (HMOX2 Produits)

Synonymes: anticorps HO-2, anticorps HO2, anticorps HMOX2, anticorps Ho-2, anticorps im:6909100, anticorps si:dkey-44g23.7, anticorps AtHO2, anticorps T9J22.22, anticorps T9J22_22, anticorps heme oxygenase 2, anticorps hmox2, anticorps ho-2, anticorps heme oxygenase 2, anticorps Heme oxygenase 2, anticorps heme oxygenase 2, putative, anticorps heme oxygenase 2a, anticorps heme oxygenase 2 L homeolog, anticorps HMOX2, anticorps Hmox2, anticorps HO2, anticorps ho2, anticorps CNF01200, anticorps CPR_0203, anticorps CGB_F5120W, anticorps hmox2a, anticorps hmox2.L

Sujet: Heme oxygenase (HO) is a microsomal enzyme involved in cellular response to oxidative stress. HO oxidatively cleaves the heme ring at the alpha methene bridge to form carbon monoxide and biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Two heme oxygenase isozymes, termed HO 1 and HO 2, have been identified so far. At the amino acid level, HO 1 and HO 2 are 42 % homologous. However, each isozyme is evolutionary highly conserved. HO 1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO 1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO 2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO 2 is the most prevalent form in most tissues, except the spleen where HO 1 levels are predominant under normal conditions.Synonyms: HO-2, HO2

ID gène: 3163

NCBI Accession: NP_002125

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis