RAPSN anticorps (N-Term)
Aperçu rapide pour RAPSN anticorps (N-Term) (ABIN401664)
Antigène
Voir toutes RAPSN AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody reacts to RAPSN.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence YQSNQTEKALQVWTK-C, from the N-Terminus of the protein sequence
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Indications d'application
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Peptide ELISA: 1/128000. Western blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0,5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))
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Autre désignation
- RAPSN / RNF205
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Sujet
- Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChRs is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region.Synonyms: 43 kDa postsynaptic protein, 43 kDa receptor-associated protein of the synapse, Acetylcholine receptor-associated 43 kDa protein, RAPsyn, RING finger protein 205
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ID gène
- 5913
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NCBI Accession
- NP_005046
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UniProt
- Q13702
Antigène
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