CPT1B anticorps (C-Term, Isoform 1)
Aperçu rapide pour CPT1B anticorps (C-Term, Isoform 1) (ABIN401668)
Antigène
Voir toutes CPT1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term, Isoform 1
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Specificité
- This antibody recognizes CPT1B (isoform 1).
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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Immunogène
- Peptide with sequence C-DIADLFQVPKAYS, from the C Terminus of the protein sequence.
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Indications d'application
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Peptide ELISA: Antibody Detecion Limit Dilution: 1/16000. Immunohistochemistry on Paraffin Sections: 3-5 μg/mL. In paraffin embedded HumanHeart, ABIN401668 shows staining of myocardial fibres in longitudinal section.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preserative and 0.5 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))
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Autre désignation
- CPT1B / CPT1-M
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Sujet
- CPT1B is a member of the carnitine/choline acetyltransferase family and is the rate controlling enzyme of the long chain fatty acid beta oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long chain fatty acyl CoAs from the cytoplasm into the mitochondria. At least four transcript variants encoding two different isoforms have been found for this gene, and one of the transcripts is bicistronic. In addition, two of the transcripts utilise alternative polyadenylation signals.Synonyms: Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, KIAA1670, muscle isoform
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ID gène
- 1375
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NCBI Accession
- NP_001138607
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UniProt
- Q92523
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Pathways
- AMPK Signaling, Monocarboxylic Acid Catabolic Process
Antigène
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