PAR1 anticorps (Internal Region)

N° du produit ABIN452298

Cet anticorps anti-PAR1 Polyclonal Chèvre (ABIN452298) détecte spécifiquement PAR1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PAR1 anticorps (Internal Region) (ABIN452298)

Antigène: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PAR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAR1 anticorps

Épitope: Internal Region

Specificité: This antibody recognizes F2R/PAR1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-TRARRPESKATNAT, from the Internal region (near N-terminus) of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: Detection limit dilution: 1/32000. Western blot: 0.5-2 μg/mL. Approx 48 kDa band observed in lysates of cell line HeLa(calculated MW of 47.8 kDa according to NP_001983.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PAR1

Antigène: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Autre désignation: Thrombin Receptor / F2R

Sujet: Thrombin receptor is a 7 transmembrane G protein coupled receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. It may play a role in platelet activation and in vascular development. Thrombin receptor expression has been documented in various blood cells, colon, kidney, liver, lung, skin, and vessel. ESTs have been isolated from adrenal, embryo, heart, heart/melanocyte/uterus, liver/spleen, pineal, skin, spleen, and vessel.Synonyms: CF2R, Coagulation factor II receptor, PAR-1, PAR1, Proteinase-activated receptor 1

ID gène: 2149

NCBI Accession: NP_001983

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus