FPR2 anticorps (AA 181-192)
Aperçu rapide pour FPR2 anticorps (AA 181-192) (ABIN452645)
Antigène
Voir toutes FPR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 181-192
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Specificité
- This monoclonal antibody reacts with the above mentioned peptide in ELISA and reacts with the 38KDa FPRL1 on Western Blot.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Attributs du produit
- Synonyms: N-formyl peptide receptor 2, FMLP-R-I, FPRH1, RFP, LXA4R, FMLP-related receptor I, Formylpeptide receptor-like 1, Lipoxin A4 receptor
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Purification
- Affinity Chromatography.
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Immunogène
- A short KLH conjugated peptide corresponding to the amino acid sequence 181-192(ASWGGTPEERLK) on Human FPRL1
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Isotype
- IgG1
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Indications d'application
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ELISA. Western Blot (1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL
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Buffer
- 0.01 M PBS, pH 7.2 without preservatives
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
Date de péremption
- 12 months
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- FPR2 (Formyl Peptide Receptor 2 (FPR2))
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Autre désignation
- FPR2 / FPRL1
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Sujet
- FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.Synonyms: FMLP-R-I, FMLP-related receptor I, FPRH1, Formyl peptide receptor-like 1, LXA4R, Lipoxin A4 receptor, N-formyl peptide receptor 2, RFP
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ID gène
- 2358
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UniProt
- P25090
Antigène
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