SDHAF1 anticorps (C-Term)
Aperçu rapide pour SDHAF1 anticorps (C-Term) (ABIN452676)
Antigène
Voir toutes SDHAF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- c-HDSTGAPETR PDGR
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Specificité
- This antibody detects Human SDHAF1 at C-term.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Canine (Dog).
Species reactivity (tested):Human. -
Purification
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
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Immunogène
- Peptide with sequence from the C-Terminus of the protein sequence according to NP_001036096.1. Genename: RNF31
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Indications d'application
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Peptide ELISA: Detection limit dilution 1/16000. Western blot: 0.3-1.0 μg/mL. Approx 19 kDa band observed in Human Brain (Cerebellum)lysates (calculated MW of 12.9 kDa according to NP_001036096.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- SDHAF1 (Succinate Dehydrogenase Complex Assembly Factor 1 (SDHAF1))
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Autre désignation
- SDHAF1
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Sujet
- The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency). SDHAF1 Plays an essential role in succinate dehydrogenase complex (SDH) assembly, a complex involved in complex II of the mitochondrial electron transport chain. Probably acts by participating in mitochondrial biosynthesis of iron-sulfur centers for complex II (Probable)Synonyms: LYR motif-containing protein 8, SDH assembly factor 1, Succinate dehydrogenase assembly factor 1 mitochondrial
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ID gène
- 644096
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NCBI Accession
- NP_001036096
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UniProt
- A6NFY7
Antigène
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