TNK2 anticorps (N-Term)
Aperçu rapide pour TNK2 anticorps (N-Term) (ABIN452711)
Antigène
Voir toutes TNK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects TNK2 / ACK1 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide selected from the N-terminal region of human ACK1
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Indications d'application
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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Autre désignation
- TNK2 / ACK1
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Sujet
- ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1
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Poids moléculaire
- 114327 Da
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ID gène
- 10188
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NCBI Accession
- NP_001010938
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UniProt
- Q07912
Antigène
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